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A hearty serving of Zesty Southern Comfort Chicken Spaghetti Bake in a rustic dish with melted cheese on top

Zesty Southern Comfort: The Ultimate Chicken Spaghetti Bake

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Experience the bold flavors of the South with this Zesty Southern Comfort Chicken Spaghetti Bake. Combining spicy, smoky seasonings with tender chicken and al dente pasta, this ultimate casserole delivers comforting warmth and a fiery kick in every bite. Perfect for weeknight dinners or weekend gatherings, this recipe is a delicious twist on traditional spaghetti that’s sure to impress.

  • Total Time: 40 minutes
  • Yield: 6 servings

Ingredients

Scale
  • 3 cups cooked and shredded chicken
  • 12 ounces spaghetti noodles
  • 1 tablespoon olive oil
  • 1 medium onion, finely chopped
  • 2 cloves garlic, minced
  • 1 can (10 oz) diced tomatoes with green chilies
  • 1 cup shredded cheddar cheese
  • 1 cup shredded Monterey Jack cheese
  • 1 teaspoon smoked paprika
  • 1 teaspoon cayenne pepper
  • 1 teaspoon dried oregano
  • Salt and pepper to taste
  • Fresh parsley for garnish

Instructions

  1. Cook the spaghetti according to package instructions until al dente. Drain and set aside. Shred the cooked chicken.
  2. In a large skillet, heat olive oil over medium heat. Add chopped onion and minced garlic; sauté 3-4 minutes until fragrant.
  3. Add diced tomatoes with green chilies to the skillet. Stir in smoked paprika, cayenne pepper, oregano, salt, and pepper. Simmer for 5 minutes.
  4. Combine cooked pasta, shredded chicken, and spicy tomato mixture in a large bowl. Mix thoroughly.
  5. Transfer the mixture to a greased baking dish. Sprinkle shredded cheeses evenly over the top.
  6. Bake in a preheated oven at 375°F (190°C) for 20-25 minutes until bubbly and golden.

Notes

  • You can adjust the amount of cayenne pepper to control the spice level.
  • Store leftovers in an airtight container for up to 3 days; reheat in the microwave or oven.
  • For a creamier casserole, stir in some shredded mozzarella or a splash of cream before baking.
  • Author: Emma Bloomfield
  • Prep Time: 15 minutes
  • Cook Time: 25 minutes
  • Category: Main Course
  • Method: Baking
  • Cuisine: Southern
  • Diet: Comfort Food

Nutrition

  • Serving Size: 1 bowl
  • Calories: 520 kcal Kcal
  • Sugar: 8 g
  • Sodium: 820 mg
  • Fat: 22 g
  • Saturated Fat: 10 g
  • Unsaturated Fat: 10 g
  • Trans Fat: 0 g
  • Carbohydrates: 65 g
  • Fiber: 4 g
  • Protein: 35 g
  • Cholesterol: 110 mg